Metabolic Phenotyping of Individuals Born Following Assisted Reproduction Techniques (IMPART)

This learn about is to match the consequences of high-fats overfeeding on metabolic risk components in children born through assisted copy applied sciences (ART) versus youngsters conceived naturally (controls). We will utilise state-of-the-art measures to characterise the physiological, endocrine and molecular responses to high fat overfeeding.
The investigators hypothesise that children conceived following ART can have greater responses to excessive-fats dietary challenge and that this can be related to DNA hypermethylation of genes that are enthusiastic about lipid metabolism.